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Technical specifications

Sensor NANOPHOX/R
Overall measuring range 0.5 - 10,000 nm

Measuring Principle
Dynamic light scattering (DLS), at 90°
Photon cross-correlation Spectroscopy (PCCS)
Light Source λ = 658 nm (red), Pout= 0 - 35 mW, adjustable1
Protection class 1
Optics two optical paths via beam splitter, alignment free
Measuring zone temperature controlled water basin, free of
condensation, vial holder on adjustable X/Y-table2
Temperature range 1 - 90°C typ.
Temperature stability ± 0.1°C
Temperature accuracy ± 0.1°C at 20°C, direct measurement at the vial
Sample vials disposable micro vials 50 µl to 2 ml
  disposable micro vials 4 ml
  glass vials (crown glass) up to 4 ml
Evaluation software WINDOX, ≥ release 5.8.1
Auto NNLS non -negative least square analysis with system-
  defined input values, automatic fit range
NNLS user defined fit-range optimisation for fine tuning
  e.g. of PSDs with multiple modes
2nd Cumulant second cumulant approximation (mean & width)
Stability analysis3 cross-correlation amplitude as stability measure

Compliance

FDA 21 CFR Part 11, ISO 22412

1 The particles inside the cuvette are illuminated by two laser beams within the same scattering volume. The intensities IA and IB are observed by two photo detectors under 90° using identical scattering vectors. The particle size information q(x) is deducted from the cross-correlation function G(τ) by three evaluation modes: auto-NNLS, NNLS and 2nd cumulant. The laser power is adjustable by software to obtain an optimum count rate.

2 The position of the scattering volume inside the cuvette can be aligned in X and Y direction for the optimum measuring conditions at the given concentration.

3 The evaluation of the stability is done by monitoring the correlation amplitude over a time series of subsequent measurements.

more ...

NANOPHOX/R
Particle size & stability analysis
with Photon Cross-correlation Spectroscopy from 0.5 nm to 10 µm

symbol: wet dispersion for suspensions or emulsions

Laser Safety

HELOS/BF with dry / wet disperser combination OASIS

All sensors of the NANOPHOX series are Class I Laser Products. Avoid direct eye exposure.

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