| Sensor | NANOPHOX/R |
| Overall measuring range | 0.5 - 10,000 nm |
Measuring Principle |
Dynamic light scattering (DLS), at 90° Photon cross-correlation Spectroscopy (PCCS) |
| Light Source | λ = 658 nm (red), Pout= 0 - 35 mW, adjustable1 |
| Protection class | 1 |
| Optics | two optical paths via beam splitter, alignment free |
| Measuring zone | temperature controlled water basin, free of condensation, vial holder on adjustable X/Y-table2 |
| Temperature range | 1 - 90°C typ. |
| Temperature stability | ± 0.1°C |
| Temperature accuracy | ± 0.1°C at 20°C, direct measurement at the vial |
| Sample vials | disposable micro vials 50 µl to 2 ml |
| disposable micro vials 4 ml | |
| glass vials (crown glass) up to 4 ml | |
| Evaluation | software WINDOX, ≥ release 5.8.1 |
| Auto NNLS | non -negative least square analysis with system- |
| defined input values, automatic fit range | |
| NNLS | user defined fit-range optimisation for fine tuning |
| e.g. of PSDs with multiple modes | |
| 2nd Cumulant | second cumulant approximation (mean & width) |
| Stability analysis3 | cross-correlation amplitude as stability measure |
Compliance |
FDA 21 CFR Part 11, ISO 22412 |
1 The particles inside the cuvette are illuminated by two laser beams within the same scattering volume. The intensities IA and IB are observed by two photo detectors under 90° using identical scattering vectors. The particle size information q(x) is deducted from the cross-correlation function G(τ) by three evaluation modes: auto-NNLS, NNLS and 2nd cumulant. The laser power is adjustable by software to obtain an optimum count rate.
2 The position of the scattering volume inside the cuvette can be aligned in X and Y direction for the optimum measuring conditions at the given concentration.
3 The evaluation of the stability is done by monitoring the correlation amplitude over a time series of subsequent measurements.
All sensors of the NANOPHOX series are Class I Laser Products. Avoid direct eye exposure.
